From within Ontario and from the Quebec border, Merrickville may be reached via Highway 401 which runs alongside the St. Lawrence River.

The exit off the 401 is #705.  From that head north up County Road #15 until you reach the village (about 46 km). 

From Ottawa, go south on Highway 416 and take exit #34 which is County Road #43. Go west on CR #43, past Kemptville to Merrickville (18 km).

As an alternative scenic route from downtown Ottawa, follow the Prince of Wales south past Manotick, all the way to North Gower; turn left onto County Rd #5 to Becketts Landing, then veer right onto County Rd #2 which will take you right to Merrickville where you can turn left at the junction with Hwy 43 and enter the Village.